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"While this approach might make sense in a more mature industry where best practices are known, AI safety is a nascent field where best practices are the subject of original scientific research. For example, despite a substantial effort from leaders in our company, including our CEO, to draft and refine Anthropic's RSP over a number of months, applying it to our first product launch uncovered many ambiguities. Our RSP was also the first such policy in the industry, and it is less than a year old."
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This reaction would contain only low concentrations of the dNTPs and relied upon brief incubation times, so that DNA synthesis would stall at random positions along the template and yield a population of DNA fragments with varying lengths. These unfinished DNA fragments were then purified and used as templates in four “minus” and four “plus” reactions.